Characterization of the novel HLA-DPA1*02:01:21 allele by sequencing-based typing

HLA. 2023 Mar;101(3):309-311. doi: 10.1111/tan.14894. Epub 2022 Nov 23.

Authors

Marine Cargou¹, Marco Andreani², Paola Giustiniani², Gwendaline Guidicelli¹, Jonathan Visentin^{1

3}

Affiliations

¹ CHU de Bordeaux, Laboratoire d'Immunologie et Immunogénétique, Hôpital Pellegrin, Place Amélie Raba Léon, Bordeaux, France.
² Laboratorio d'Immunogenetica dei Trapianti, IRCCS Ospedale Pediatrico Bambino Gesù, Roma, Italy.
³ Univ. Bordeaux, CNRS, ImmunoConcEpT, Bordeaux, France.

Abstract

HLA-DPA1*02:01:21 differs from HLA-DPA1*02:01:01:03 by one nucleotide substitution in codon 190 in exon 4.

Keywords: HLA-DPA1*02:01:21; HLA; novel allele; sequencing-based typing.

© 2022 The Authors. HLA: Immune Response Genetics published by John Wiley & Sons Ltd.

MeSH terms

Alleles
HLA-DP alpha-Chains* / genetics
Histocompatibility Testing
Humans
Sequence Alignment
Sequence Analysis, DNA

Substances

HLA-DPA1 antigen
HLA-DP alpha-Chains