Secondhand smoke exposure is independently associated with stroke among non-smoking adults in West Africa

J Neurol Sci. 2022 Dec 15:443:120489. doi: 10.1016/j.jns.2022.120489. Epub 2022 Nov 8.

Abstract

Background: Stroke is a leading cause of disability and mortality worldwide, but little is known about the contribution of secondhand smoke exposure (SHSE) to stroke epidemiology among indigenous Africans.

Objective: To evaluate the association of SHSE with stroke among indigenous Africans.

Methods: We analyzed the relationship of SHSE with stroke among 2990 case-control pairs of adults who had never smoked (identified in the SIREN study) using conditional logistic regression at a two-sided P < 0.05.

Results: Multivariable-adjusted odds ratio and 95% confidence interval; 1.25 (1.04, 1.50; P = 0.02) revealed SHSE was positively associated with stroke independent of stroke subtypes.

Conclusion: Culturally relevant primary prevention strategies targeted at SHSE might be promising in preventing stroke among Africans.

Keywords: Haemorrhagic stroke; Ischaemic stroke; SIREN; Secondhand smoking; Stroke.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, N.I.H., Extramural

MeSH terms

  • Adult
  • Africa, Western / epidemiology
  • Black People
  • Humans
  • Odds Ratio
  • Stroke* / epidemiology
  • Tobacco Smoke Pollution* / adverse effects

Substances

  • Tobacco Smoke Pollution