Surveying the Landscape: A Review of Longitudinal Traumatic Brain Injury Studies in Service Member and Veteran Populations

J Neurotrauma. 2023 Jun;40(11-12):1060-1074. doi: 10.1089/neu.2022.0237. Epub 2023 Jan 17.

Abstract

Traumatic brain injury (TBI) is known to be a signature wound of the post-9/11 conflicts. In response, the U.S. Department of Defense (DOD) and other federal organizations have directed significant investments toward TBI research on characterizing injury populations and understanding long-term outcomes. To address legislative requirements and research gaps, several observational, longitudinal TBI studies were initiated as an effective means of investigating TBI clinical management, outcomes, and recovery. This review synthesizes the landscape (i.e., requirements and gaps, infrastructure, geography, timelines, TBI severity definitions, military and injury populations of interest, and measures) of DOD-funded longitudinal TBI studies being conducted in service member and veteran (SMV) populations. Based on the landscape described here, we present recommended actions and solutions that would allow a consolidated and cooperative future state of longitudinal TBI research, optimized continued investments, and advances in the state of the science without redundancy.

Keywords: landscape; longitudinal studies; military research; service member; traumatic brain injury; veteran.

Publication types

  • Review
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Brain Injuries*
  • Brain Injuries, Traumatic* / epidemiology
  • Brain Injuries, Traumatic* / therapy
  • Humans
  • Longitudinal Studies
  • Military Personnel*
  • Veterans*