Exploring developmental trajectories throughout adolescence of children with autism spectrum disorder without intellectual disability

J Neural Transm (Vienna). 2023 Mar;130(3):299-312. doi: 10.1007/s00702-022-02554-w. Epub 2022 Nov 16.

Abstract

Characterizing the developmental trajectories of children with autism spectrum disorder (ASD) throughout adolescence and across different domains of functioning offers opportunities to improve long-term outcomes. This prospective study explored, for the first time, the evolution of children with ASD-without intellectual disability (ID) in terms of socio-adaptative skills, learning behaviors, executive functioning (EF), and internalizing/externalizing problems, compared to typically developing (TD) peers. Forty-five children with ASD-without ID and 37 matched TD children (aged 7-11) were assessed at baseline and after 5 years. Parents and teachers completed measures on theory of mind (ToM), socialization, daily living skills, learning style, EF, and emotional/behavioural difficulties at both time points. On all the domains assessed, the ASD group performed significantly worse than the TD group, both in childhood and adolescence. Specific changes were noted between baseline and follow-up assessment on adaptive skills, prosocial behavior, emotional control, inhibit, working memory and monitoring. Group membership (ASD/TD) was influenced by peer relationships and inhibit EF variables. These findings have implications for clinical and school settings.

Keywords: Adaptive skills; Autism; Learning behaviors; Mental health problems; Prospective; Theory of mind.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Autism Spectrum Disorder* / psychology
  • Child
  • Executive Function
  • Humans
  • Intellectual Disability*
  • Memory, Short-Term
  • Prospective Studies