Background: Across the world, 25-hydroxyvitamin D (25-OHD) deficiency is a major health problem associated with many chronic diseases in the geriatric population. Prior to this study, there were no data regarding 25-OHD levels among individuals over the age of 65 in Turkey. The aim of this study was to assess 25-OHD levels and seasonal variations in these values among people over the age of 65 in Turkey.
Methods: This study included vitamin D measurements taken in 2016, 2017, and 2018 from the Turkish population over the age of 65. The age, gender, and seasonal average data of the study population were defined. The study data were obtained from the database of the Ministry of Health, and a Kolmogorov-Smirnov test was used to assess the distribution of the data. Medians and interquartile ranges (IQRs) were calculated for all categories, as the data were nonparametric.
Results: The number of vitamin D measurements taken from the geriatric individuals included in this study was 305,329 for 2016, 576,452 for 2017, and 752,837 for 2018. The medians and IQRs of the 25-OHD levels in this population were 16 μg/L (IQR 7.45-24.55 μg/L) for 2016, 16.1 μg/L (IQR 7.8-24.4 μg/L) for 2017, and 16.4 μg/L (IQR 8.95-23.85 μg/L) for 2018.
Conclusions: While the 25-OHD levels of older men tended to increase during the period of seasonal sunlight in Turkey, this variability was observed in elderly women. This suggests that older women tend to live more sedentary lives and have insufficient sun exposure. Overall, the median 25-OHD levels of individuals over the age of 65 tended to decrease each year.
Uvod: Širom sveta, nedostatak 25-hidroksivitamina D (25-OHD) je veliki zdravstveni problem povezan sa mnogim hroničnim bolestima u gerijatrijskoj populaciji. Pre ove studije, nije bilo podataka o nivoima 25-OHD me u pojedincima starijim od 65 godina u Turskoj. Cilj ove studije je bio da se proceni nivo 25-OHD i sezonske varijacije ovih vrednosti kod ljudi starijih od 65 godina u Turskoj.
Metode: Ova studija je uključila merenja vitamina D uzeta 2016, 2017. i 2018. godine od turske populacije starije od 65 godina. Definisani su podaci o starosti, polu i sezonskom proseku ispitivane populacije. Podaci studije su dobijeni iz baze podataka Ministarstva zdravlja, a za procenu distribucije podataka korišćen je Kolmogorov-Smirnov test. Medijani i interkvartilni rasponi (IKR) su izračunati za sve kategorije, pošto su podaci bili neparametrijski.
Rezultati: Broj merenja vitamina D uzetih od gerijatrijskih pojedinaca uključenih u ovu studiju bio je 305.329 za 2016, 576.452 za 2017. i 752.837 za 2018. Medijani i IKR nivoa 25-OHD u ovoj populaciji su bili 16 mg/L IKR 7,45-24,55 mg/L) za 2016, 16,1 mg/L (IKR 7,8-24,4 mg/L) za 2017, i 16,4 mg/L (IKR 8,95-23,85 mg/L) za 2018.
Zaključak: Dok je nivo 25-OHD kod starijih muškaraca imao tendenciju povećanja tokom perioda sezonske sunčeve svetlosti u Turskoj, ova varijabilnost je primećena kod starijih žena. Ovo sugeriše da starije žene imaju tendenciju da žive više sedentarno i da su nedovoljno izložene suncu. Sve u svemu, srednji nivoi 25-OHD kod osoba starijih od 65 godina su se smanjivale svake godine.
Keywords: 25-OH vitamin D; big data; geriatry; seasons; sunbathing time; vitamin D deficiency.
2022 Murat Çağlayan, Cigdem Sonmez, Mehmet Senes, Ataman Gonel, Ozlem Gulbahar, Nurbanu Bursa, Derun Taner, Osman Celik, Fidanci Ali Aykut, Ulgu Mustafa Mahir, Abdulvahit Sozuer, Naim Ata, Suayip Birinci, published by CEON/CEES.