Reconstruction of vertical alveolar ridge deficiencies utilizing a high-density polytetrafluoroethylene membrane /clinical impact of flap dehiscence on treatment outcomes: case series/

BMC Oral Health. 2022 Nov 15;22(1):490. doi: 10.1186/s12903-022-02513-7.

Abstract

Objectives: The aim of this study was to evaluate the effects of membrane exposure during vertical ridge augmentation (VRA) utilizing guided bone regeneration with a dense polytetrafluoroethylene (d-PTFE) membrane and a tent-pole space maintaining approach by registering radiographic volumetric, linear and morphological changes.

Methods: In 8 cases alveolar ridge defects were accessed utilizing a split-thickness flap design. Following flap elevation VRA was performed with tent-pole space maintaining approach utilizing the combination of a non-reinforced d-PTFE membrane and a composite graft (1:1 ratio of autogenous bone chips and bovine derived xenografts). Three-dimensional radiographic evaluation of hard tissue changes was carried out with the sequence of cone-beam computed tomography (CBCT) image segmentation, spatial registration and 3D subtraction analysis.

Results: Class I or class II membrane exposure was observed in four cases. Average hard tissue gain was found to be 0.70 cm3 ± 0.31 cm3 and 0.82 cm3 ± 0.40 cm3 with and without membrane exposure resulting in a 17% difference. Vertical hard tissue gain averaged 4.06 mm ± 0.56 mm and 3.55 mm ± 0.43 mm in case of submerged and open healing, respectively. Difference in this regard was 14% between the two groups. Horizontal ridge width at 9-month follow-up was 5.89 mm ± 0.51 mm and 5.61 mm ± 1.21 mm with and without a membrane exposure respectively, resulting in a 5% difference.

Conclusions: With the help of the currently reported 3D radiographic evaluation method, it can be concluded that exposure of the new-generation d-PTFE membrane had less negative impact on clinical results compared to literature data reporting on expanded polytetrafluoroethylene membranes.

Keywords: 3D evaluation; CBCT analysis; D-PTFE; Guided bone regeneration; Membrane exposure; Vertical ridge augmentation; Wound dehiscence.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alveolar Bone Loss* / diagnostic imaging
  • Alveolar Bone Loss* / drug therapy
  • Alveolar Bone Loss* / surgery
  • Alveolar Process / surgery
  • Alveolar Ridge Augmentation* / methods
  • Animals
  • Bone Transplantation / methods
  • Cattle
  • Dental Implantation, Endosseous / methods
  • Guided Tissue Regeneration, Periodontal / methods
  • Humans
  • Membranes, Artificial
  • Polytetrafluoroethylene / therapeutic use

Substances

  • Polytetrafluoroethylene
  • Membranes, Artificial