Consecutive photochemical reactions enabled by a dual flow reactor coil strategy

Chem Commun (Camb). 2022 Nov 29;58(95):13274-13277. doi: 10.1039/d2cc05601a.

Abstract

The application of a dual reactor coil for consecutive photochemical reactions is presented in continuous flow mode. This strategy enables for the first time the use of a single LED-based light source to perform two distinct photochemical reactions in an uninterrupted fashion. This approach is demonstrated for the telescoped synthesis and functionalisation of drug-like quinolines and compared to alternatives exploiting two photochemical reactor set-ups operated in sequence. The presented strategy enables the intensified exploitation of photochemical reactions in modern synthesis.