Intravascular Imaging-Derived Physiology-Basic Principles and Clinical Application

Annemieke C Ziedses des Plantes; Alessandra Scoccia; Frank Gijsen; Gijs van Soest; Joost Daemen

doi:10.1016/j.iccl.2022.09.008

Intravascular Imaging-Derived Physiology-Basic Principles and Clinical Application

Interv Cardiol Clin. 2023 Jan;12(1):83-94. doi: 10.1016/j.iccl.2022.09.008.

Authors

Annemieke C Ziedses des Plantes¹, Alessandra Scoccia¹, Frank Gijsen², Gijs van Soest², Joost Daemen³

Affiliations

¹ Department of Cardiology, Thoraxcenter, Erasmus University Medical Center, P.O. Box 2040, 3000 CA, Rotterdam, the Netherlands.
² Department of Biomedical Engineering, Erasmus University Medical Center, P.O. Box 2040, 3000 CA, Rotterdam, the Netherlands.
³ Department of Cardiology, Thoraxcenter, Erasmus University Medical Center, P.O. Box 2040, 3000 CA, Rotterdam, the Netherlands. Electronic address: j.daemen@erasmusmc.nl.

PMID: 36372464
DOI: 10.1016/j.iccl.2022.09.008

Abstract

Intravascular imaging-derived physiology is emerging as a promising tool allowing simultaneous anatomic and functional lesion assessment. Recently, several optical coherence tomography-based and intravascular ultrasound-based fractional flow reserve (FFR) indices have been developed that compute FFR through computational fluid dynamics, fluid dynamics equations, or machine-learning methods. This review aims to provide an overview of the currently available intravascular imaging-based physiologic indices, their diagnostic performance, and clinical application.

Keywords: Functional lesion assessment; IVUS-based FFR; OCT-based FFR; OFR; Percutaneous coronary intervention; Virtual FFR.

Publication types

Review

MeSH terms

Coronary Stenosis*
Coronary Vessels / diagnostic imaging
Fractional Flow Reserve, Myocardial*
Humans
Tomography, Optical Coherence / methods
Ultrasonography, Interventional / methods