Congenital coronary artery-left ventricular multiple micro-fistulas and hypertrophic cardiomyopathy: a case report and literature review

BMC Cardiovasc Disord. 2022 Nov 12;22(1):483. doi: 10.1186/s12872-022-02926-w.

Abstract

Background: Coronary artery-left ventricular multiple micro-fistulas (CA-LVMMFs) is a rare congenital vascular anomaly that may present with no obvious clinical symptoms or a typical angina attack. CA-LVMMFs is usually found unexpectedly during coronary angiography (CAG).

Case presentation: We report a case of a 65-year-old man admitted to the hospital with acute coronary syndrome. CA-LVMMFs was found during coronary angiography. Echocardiography showed apical hypertrophy and blood flow signals were seen in the apical myocardium, connected with the left ventricle. We searched the MEDLINE database and found 39 relevant reports. We made statistics on the clinical characteristics of these patients and found half involved hypertrophy or perfusion defects in the ventricular septum or apex.

Conclusion: As a rare congenital anomaly, the effect of CA-LVMMFs on patients is unclear. By reporting a case and summarizing literature reports, we found that CA-LVMMFs may be associated with myocardial hypertrophy, especially ventricular septal and apical hypertrophy.

Keywords: Case report; Congenital coronary artery-left ventricular multiple micro-fistulas; Hypertrophic cardiomyopathy.

Publication types

  • Review
  • Case Reports

MeSH terms

  • Aged
  • Angina Pectoris
  • Cardiomyopathy, Hypertrophic* / diagnosis
  • Coronary Artery Disease* / complications
  • Fistula*
  • Heart Defects, Congenital* / complications
  • Heart Ventricles / diagnostic imaging
  • Humans
  • Hypertrophy / complications
  • Male