Endoplasmic Reticulum Stress and Oxidative Stress in Inflammatory Diseases

DNA Cell Biol. 2022 Nov;41(11):924-934. doi: 10.1089/dna.2022.0353. Epub 2022 Sep 14.

Abstract

Endoplasmic reticulum (ER) stress and oxidative stress (OS) are often related states in cells as part of normal physiology but more frequently manifested in the pathophysiology of many diseases, particularly diseases involving acute or chronic inflammation. In this study, we reviewed recent findings about the role of ER stress and OS in the pathogenesis of inflammatory diseases.

Keywords: endoplasmic reticulum stress; inflammation; oxidative stress; reactive oxygen species.

Publication types

  • Review

MeSH terms

  • Endoplasmic Reticulum Stress* / physiology
  • Humans
  • Inflammation
  • Oxidative Stress* / physiology
  • Reactive Oxygen Species

Substances

  • Reactive Oxygen Species