Hypertension Across a Woman's Life Cycle

Curr Hypertens Rep. 2022 Dec;24(12):723-733. doi: 10.1007/s11906-022-01230-4. Epub 2022 Nov 9.

Abstract

Purpose of review: We reviewed the effects of hypertension and the means to prevent and treat it across the spectrum of a woman's lifespan and identified gaps in sex-specific mechanisms contributing to hypertension in women that need to be addressed.

Recent findings: Hypertension continues to be an important public health problem for women across all life stages from adolescence through pregnancy, menopause, and older age. There remain racial, ethnic, and socioeconomic differences in hypertension rates not only overall but also between the sexes. Blood pressure cutoffs during pregnancy have not been updated to reflect the 2017 ACC/AHA changes due to a lack of data. Additionally, the mechanisms behind hypertension development in menopause, including sex hormones and genetic factors, are not well understood. In the setting of increasing inactivity and obesity, along with an aging population, hypertension rates are increasing in women. Screening and management of hypertension throughout a women's lifespan are necessary to reduce the burden of cardiovascular disease, and further research to understand sex-specific hypertension mechanisms is needed.

Keywords: Hypertension; Life cycle; Sex differences; Women.

Publication types

  • Review

MeSH terms

  • Adolescent
  • Aged
  • Aging
  • Animals
  • Cardiovascular Diseases* / prevention & control
  • Female
  • Humans
  • Hypertension* / epidemiology
  • Life Cycle Stages
  • Male
  • Menopause
  • Pregnancy