Alterations in the human oral microbiome in cholangiocarcinoma

Ben-Chen Rao; Gui-Zhen Zhang; Ya-Wen Zou; Tong Ren; Hong-Yan Ren; Chao Liu; Zu-Jiang Yu; Zhi-Gang Ren

doi:10.1186/s40779-022-00423-x

Alterations in the human oral microbiome in cholangiocarcinoma

Mil Med Res. 2022 Nov 8;9(1):62. doi: 10.1186/s40779-022-00423-x.

Authors

Ben-Chen Rao^{1

2

3}, Gui-Zhen Zhang^{1

2

3}, Ya-Wen Zou^{1

2

3}, Tong Ren⁴, Hong-Yan Ren⁵, Chao Liu⁵, Zu-Jiang Yu^{6

7}, Zhi-Gang Ren^{8

9

10}

Affiliations

¹ Department of Infectious Diseases, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China.
² Jinan Microecological Biomedicine Shandong Laboratory, Jinan, 250000, China.
³ Gene Hospital of Henan Province, Precision Medicine Center, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China.
⁴ Department of Pharmacy, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China.
⁵ Shanghai Mobio Biomedical Technology Co., Ltd., Shanghai, 201111, China.
⁶ Department of Infectious Diseases, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China. johnyuem@zzu.edu.cn.
⁷ Gene Hospital of Henan Province, Precision Medicine Center, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China. johnyuem@zzu.edu.cn.
⁸ Department of Infectious Diseases, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China. fccrenzg@zzu.edu.cn.
⁹ Jinan Microecological Biomedicine Shandong Laboratory, Jinan, 250000, China. fccrenzg@zzu.edu.cn.
¹⁰ Gene Hospital of Henan Province, Precision Medicine Center, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China. fccrenzg@zzu.edu.cn.

No abstract available

Keywords: 16S rRNA MiSeq sequencing; Cholangiocarcinoma; Diagnostic biomarker; Oral microbiome; Random forest model.

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Bacteria
Bile Duct Neoplasms*
Bile Ducts, Intrahepatic
Cholangiocarcinoma*
Humans
Microbiota*