Effect of treatment zone decentration on axial length growth after orthokeratology

Shuxian Zhang; Hui Zhang; Lihua Li; Xiaoyan Yang; Shumao Li; Xuan Li

doi:10.3389/fnins.2022.986364

Effect of treatment zone decentration on axial length growth after orthokeratology

Front Neurosci. 2022 Oct 20:16:986364. doi: 10.3389/fnins.2022.986364. eCollection 2022.

Authors

Shuxian Zhang^{1

2

3

4}, Hui Zhang³, Lihua Li^{1

2

3}, Xiaoyan Yang^{1

2

3}, Shumao Li³, Xuan Li^{1

2

4}

Affiliations

¹ Clinical College of Ophthalmology, Tianjin Medical University, Tianjin, China.
² Tianjin Key Lab of Ophthalmology and Visual Science, Tianjin Eye Hospital, Tianjin, China.
³ Tianjin Eye Hospital Optometric Center, Tianjin, China.
⁴ Nankai University Affiliated Eye Hospital, Nankai University, Tianjin, China.

Abstract

Objective: To study the effect of treatment zone (TZ) decentration on axial length growth (ALG) in adolescents after wearing the orthokeratology lenses (OK lenses).

Materials and methods: This retrospective clinical study selected 251 adolescents who were fitted OK lenses at the Clinical College of Ophthalmology, Tianjin Medical University (Tianjin, China) from January 2018-December 2018 and wore them continuously for >12 months. The age of the subjects was 8-15 years, spherical equivalent (SE): -1.00 to -5.00 diopter (D), and astigmatism ≤ 1.50 D. The corneal topography were recorded at baseline and 1-, 6-, and 12-month visits, and the axial length (AL) were recorded at baseline and 6-, 12-month visits. The data of the right eye were collected for statistical analysis.

Results: The subjects were divided into three groups according to the decentration distance of the TZ after wearing lenses for 1 month: 56 cases in the mild (<0.5 mm), 110 in the moderate (0.5-1.0 mm), and 85 in the severe decentration group (>1.0 mm). A significant difference was detected in the ALG between the three groups after wearing lenses for 6 and 12 months (F = 10.223, P < 0.001; F = 13.380, P < 0.001, respectively). Among these, the 6- and 12-month ALG of the mild decentration group was significantly higher than that of the other two groups. Multivariable linear regression analysis showed that age, baseline SE, and 1-month decentration distance associated with the 12-month ALG (P < 0.001, P < 0.001, and P = 0.001, respectively).

Conclusion: The decentration of the TZ of the OK lens affected the growth of the AL in adolescents, i.e., the greater the decentration, the slower the ALG.

Keywords: axial length; decentration; myopia; orthokeratology; refraction.