Research advances in prevention and treatment of burn wound deepening in early stage

Meiqi Lu; Jie Zhao; Xiaochuan Wang; Jingjuan Zhang; Fei Shan; Duyin Jiang

doi:10.3389/fsurg.2022.1015411

Research advances in prevention and treatment of burn wound deepening in early stage

Front Surg. 2022 Oct 21:9:1015411. doi: 10.3389/fsurg.2022.1015411. eCollection 2022.

Authors

Meiqi Lu¹, Jie Zhao², Xiaochuan Wang², Jingjuan Zhang¹, Fei Shan², Duyin Jiang^{1

2}

Affiliations

¹ Department of Burns and Plastic Surgery, The Second Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China.
² Department of Emergency Medical Center, The Second Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China.

Abstract

The burn wound is a dynamic living environment that is affected by many factors. It may present a progressive expansion of necrosis into the initially viable zone of stasis within a short time postburn. Therefore, how to salvage of the zone of stasis is of crucial importance in prevention and treatment strategies of burn wound progressive deepening. This review focuses on the cellular basis of tissue injury and the current progress of prevention and treatment strategies of burn wound progressive deepening, in order to provide references for the treatment of burn wounds in the early phase.

Keywords: burns; mechanism; mesenchymal stem cells; wound healing; wound progression.

Publication types

Review