Automatic Coregistration Between Coronary Angiography and Intravascular Optical Coherence Tomography: Feasibility and Accuracy

Hui Qin; Chunming Li; Yingguang Li; Jiayue Huang; Fan Yang; Takashi Kubo; Takashi Akasaka; Changyan Xiao; Juan Luis Gutiérrez-Chico; Shengxian Tu

doi:10.1016/j.jacasi.2021.07.002

Automatic Coregistration Between Coronary Angiography and Intravascular Optical Coherence Tomography: Feasibility and Accuracy

JACC Asia. 2021 Sep 21;1(2):274-278. doi: 10.1016/j.jacasi.2021.07.002. eCollection 2021 Sep.

Authors

Hui Qin^{1

2}, Chunming Li², Yingguang Li³, Jiayue Huang², Fan Yang², Takashi Kubo⁴, Takashi Akasaka⁴, Changyan Xiao¹, Juan Luis Gutiérrez-Chico⁵, Shengxian Tu²

Affiliations

¹ College of Electrical and Information Engineering, Hunan University, Changsha, China.
² Biomedical Instrument Institute, School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, China.
³ Kunshan Industrial Technology Research Institute Co Ltd, Kunshan, China.
⁴ Department of Cardiovascular Medicine, Wakayama Medical University, Wakayama, Japan.
⁵ Cardiology Department, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Abstract

This study sought to evaluate a novel approach for automatic coregistration of optical coherence tomography (OCT) and coronary angiography. Lumen diameters and side branches from both coronary angiography and OCT were used to create 2 feature sets. Subsequently, a 2-step coregistration approach was performed on the feature sets for matching of each OCT cross section on the angiographic centerline. For validation, all side branches with ≥1.0 mm diameter were identified and used as paired fiduciary landmarks. Geographical error was defined as the distance between the automatically coregistered and the true-paired landmarks. Altogether 212 vessels from 181 patients were analyzed. Mismatch of coronary angiography and OCT occurred in 64 of 1,530 reference landmarks. Median geographical error was 0.32 (interquartile range: 0.00-0.56) mm. The mean time for coregistration was 20.69 ± 1.07 seconds. In conclusion, fast and automatic coregistration of OCT and angiography using a single standard angiographic loop is feasible and accurate.

Keywords: CAG, coronary angiography; IQR, interquartile range; IVUS, intravascular ultrasound; LAD, left anterior descending coronary artery; OCT, optical coherence tomography; SB, side branch; angiography; image registration; optical coherence tomography; percutaneous coronary intervention.