Patterns of respiratory tract infections in children under 5 years of age in a low-middle-income country

Nehal M El-Koofy; Mortada H El-Shabrawi; Basant A Abd El-Alim; Marwa M Zein; Nora E Badawi

doi:10.1186/s42506-022-00118-0

Patterns of respiratory tract infections in children under 5 years of age in a low-middle-income country

J Egypt Public Health Assoc. 2022 Nov 7;97(1):22. doi: 10.1186/s42506-022-00118-0.

Authors

Nehal M El-Koofy¹, Mortada H El-Shabrawi¹, Basant A Abd El-Alim¹, Marwa M Zein², Nora E Badawi¹

Affiliations

¹ Department of Pediatrics, Faculty of Medicine, Cairo University, Cairo, Egypt.
² Department of Public Health and Community Medicine, Faculty of Medicine, Cairo University, Cairo, Egypt. marwa.zein@kasralainy.edu.eg.

Abstract

Background: Respiratory tract infections (RTIs) are among the most commonly encountered major public health problems, with a higher prevalence of lower RTIs among children and more generally the poor. The present study aimed to describe the pattern of respiratory tract infections in Egyptian children aged under 5 years and explore possible associations between socio-demographics and nutritional status and types of RTIs.

Methods: Over 6 months beginning in September 2018 (including one winter season), a cross-sectional, observational, epidemiological study was conducted on a sample of patients with upper and lower RTIs diagnosed clinically and/or radiologically in the outpatient clinics at Cairo University Children's Hospital in Egypt. An interview questionnaire was employed to collect socio-demographic and nutritional data. Heights/lengths and weights were measured and analyzed using the World Health Organization's (WHO) Anthro Plus [Computer Program]. Patients with pneumonia (n = 28) were compared to 97 healthy children of the same age and sex.

Results: The total number of children diagnosed with upper and lower respiratory infections was 611. Malnutrition was present in 12.4% of all children with upper and lower RTIs. Lower RTI and malnutrition were substantially more prevalent among children aged under 2 years (p = 0.048 and p < 0.001, respectively). The strongest predictor of lower RTI was a younger age (OR 0.797, CI 0.713-0.89, p < 0.001).

Conclusion: At our center, approximately one-third of infections in under-fives were lower RTI. Malnutrition was one of the significant risk factors for lower RTI in children below 2 years. The nutritional status of infants and young children should be improved by encouraging exclusive breastfeeding during the first 6 months of life and strengthening the healthcare and nutritional counseling available for vulnerable children, particularly in rural regions.

Keywords: Breast feeding; Children below 5 years; Crowding index; Lower respiratory tract infections; Pneumonia; Upper respiratory tract infections; malnutrition.