Neuromuscular Weakness in Intensive Care

Deepa Malaiyandi; Elysia James

doi:10.1016/j.ccc.2022.06.004

Neuromuscular Weakness in Intensive Care

Crit Care Clin. 2023 Jan;39(1):123-138. doi: 10.1016/j.ccc.2022.06.004. Epub 2022 Oct 7.

Authors

Deepa Malaiyandi¹, Elysia James²

Affiliations

¹ Division of Neurocritical Care, Department of Neurology, University of Toledo College of Medicine, UT/PPG Neurosciences Center, 2130 West Central Avenue, Suite 201, Room 2355, Toledo, OH 43606, USA. Electronic address: Deepa.malaiyandi@utoledo.edu.
² Division of Neurocritical Care, Department of Neurology, University of Toledo College of Medicine, UT/PPG Neurosciences Center, 2130 West Central Avenue, Suite 201, Room 2355, Toledo, OH 43606, USA.

PMID: 36333027
DOI: 10.1016/j.ccc.2022.06.004

Abstract

Diseases of the peripheral nervous system create an additional diagnostic conundrum within the intensive care setting. Causes are vast, presentations are myriad, and symptoms are often ill-defined or misidentified. Care benefits from a multidisciplinary approach including a neuromuscular specialist, rehabilitation services, and a specialty pharmacist in addition to the neurocritical care team. In general, survivors achieve a good functional recovery relative to their preintensive care unit baseline.

Keywords: Acute myopathy; Critical illness associated weakness; Guillain-Barre syndrome; Intensive care unit acquired weakness; Myasthenic crisis; Neuromuscular respiratory failure; Neuromuscular weakness.

Publication types

Review

MeSH terms

Critical Care
Critical Illness
Humans
Intensive Care Units
Muscle Weakness / diagnosis
Muscle Weakness / etiology
Muscle Weakness / therapy
Neuromuscular Diseases* / diagnosis
Neuromuscular Diseases* / therapy