Functional renal collecting ducts from human PSCs

Shunsuke Tanigawa; Ryuichi Nishinakamura

doi:10.1016/j.stem.2022.10.006

Functional renal collecting ducts from human PSCs

Cell Stem Cell. 2022 Nov 3;29(11):1510-1512. doi: 10.1016/j.stem.2022.10.006.

Authors

Shunsuke Tanigawa¹, Ryuichi Nishinakamura²

Affiliations

¹ Department of Kidney Development, Institute of Molecular Embryology and Genetics, Kumamoto University, Kumamoto 860-0811, Japan.
² Department of Kidney Development, Institute of Molecular Embryology and Genetics, Kumamoto University, Kumamoto 860-0811, Japan. Electronic address: ryuichi@kumamoto-u.ac.jp.

PMID: 36332567
DOI: 10.1016/j.stem.2022.10.006

Abstract

Collecting ducts in the kidney control the balance of water and electrolytes, as well as pH of the urine to maintain body homeostasis. Shi et al.¹ recently reported in Nature Biotechnology a protocol to generate functional collecting duct cells from human pluripotent stem cells.

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MeSH terms

Homeostasis
Humans
Kidney
Kidney Tubules, Collecting* / physiology