Creating a large-scale functional system from a group of bio-nanomachines is a key objective for engineering innovative applications. This paper aims to create a large-scale system of bio-nanomachines and proposes a collective rotational motion model to describe their behaviour. The proposed model is based on the notion that spinning objects are stable against perturbations, meaning that a rotating cluster of bio-nanomachines may be stable and suitable for large-scale bio-nanomachine systems to be engineered for applications in dynamic and noisy environments. In developing the model, we draw inspiration from biological pattern formation, where biological entities interact chemically and physically to form a functional structure. Accordingly, we develop a collective rotational motion model of bio-nanomachines based on their chemical and physical interactions. Through modeling and simulations, we gain insight into the design and engineering of rotating clusters of bio-nanomachines. This paper demonstrates the importance of physical interactions in creating system-level functionality from a group of bio-nanomachines, giving rise to new challenges and opportunities in molecular communication research.