Are We Scared of Clinical Trials if Not Sufficiently Informed and Educated?

Lejla Burnazovic-Ristic; Andrea Todic; Sanita Maleskic Kapo; Jasna Kusturica; Aida Kulo Cesic; Svjetlana Loga-Zec; Izeta Aganovic-Musinovic; Maida Rakanovic-Todic

doi:10.2147/AMEP.S375904

Are We Scared of Clinical Trials if Not Sufficiently Informed and Educated?

Adv Med Educ Pract. 2022 Oct 27:13:1359-1366. doi: 10.2147/AMEP.S375904. eCollection 2022.

Authors

Lejla Burnazovic-Ristic¹, Andrea Todic², Sanita Maleskic Kapo¹, Jasna Kusturica¹, Aida Kulo Cesic¹, Svjetlana Loga-Zec¹, Izeta Aganovic-Musinovic³, Maida Rakanovic-Todic¹

Affiliations

¹ Department of Pharmacology and Toxicology, Medical Faculty University of Sarajevo, Sarajevo, Bosnia and Herzegovina.
² Sendcloud B.V., Eindhoven, the Netherlands.
³ Immunology Department, Medical Faculty University of Sarajevo, Sarajevo, Bosnia and Herzegovina.

Abstract

Purpose: Educational interventions have already been shown to positively affect awareness of clinical trials (CTs) among medical students. We aimed to explore basic knowledge and attitudes about CTs among medical students in terms of educational interventions that should be reflected in their further involvement in performing CTs and their role in raising awareness about CTs.

Methods: This cross-sectional, self-report anonymous online survey involved undergraduate medical students of the Medical Faculty University of Sarajevo enrolled in classes held within the Department of Pharmacology and Toxicology in the academic year 2015-2016. To include all accessible subjects for better representation of the whole population, consecutive sampling was applied.

Results: Among 142 students who completed questionnaire, 50% of them expressed partial or full agreement with the questionnaire statement that they were satisfied with the available information on CTs. Only 38% said they would participate in a CT, 21% would not, while 41% were not sure. Positive correlations were detected for composite subscale scores of agreement with questionnaire statements conveying the student's knowledge about ethical and legal aspects of CTs and their perception about reliability/integrity and impact of CTs on medical practice.

Conclusion: Students have knowledge of the basic design and ethical aspects of CTs. Positive attitudes toward the impact of CTs on medical practice were shown in students of higher years of study, where educational intervention of additional knowledge of CTs was inserted and those students expressed better knowledge of CTs. However, no significant impact was detected between knowledge and willingness to participate in CTs, irrespective of years of study, reflecting the third of students that would participate in CTs. Changes in medical curricula led to the change in students' knowledge and attitudes regarding CTs as well as their involvement in CTs.

Keywords: education; intervention; knowledge; questionnaire; students.