Subjective voice change was associated with appendicular skeletal muscle mass in elderly men, but not in women: A cross-sectional study

Abstract

Objectives: To investigate the relationship between subjective voice changes and appendicular skeletal muscle in the elderly in Korea.

Design: Retrospective cross-sectional study.

Setting: Population-based survey data were collected by the Korean National Health and Nutrition Examination Survey between January 2009 and December 2011.

Participants: A total of 2611 participants (1081 men and 1530 women) aged 65 to 80 years were enrolled in the Korean National Health and Nutrition Examination Survey from 2009 to 2011. A 70-degree laryngeal endoscopy was performed to check for abnormalities in the larynx, while dual-energy x-ray absorptiometry was utilised to measure appendicular skeletal muscle mass. The correlation between subjective voice change and appendicular skeletal muscle index (ASMI) was analysed using a linear-by-linear association test and logistic regression analysis.

Results: When comparing ASMI according to the presence or absence of subjective voice change, elderly men showed significantly lower ASMI values when subjective voice change was present (p = .021). However, in women, the ASMI was not significantly lower in the presence of subjective voice changes (p = .365). We confirmed that subjective voice change was significantly lower in the highest quintile of ASMI compared to lowest quintile of ASMI in the men using logistic regression analysis (B 0.281, 95% confident interval 0.082-0.964, p < .044).

Conclusions: This study has shown that in Korean men aged >65 years, subjective voice abnormality significantly increased as skeletal muscle mass decreased. Further longitudinal studies are needed to determine whether a correlation exists between objective voice test results and ASMI.

Keywords: Korean; appendicular skeletal muscle; elderly; voice.