Optimization of biomass and target protein yield for Phase III clinical trial to evaluate Angiotensin Converting Enzyme 2 expressed in lettuce chloroplasts to reduce SARS-CoV-2 infection and transmission

Plant Biotechnol J. 2023 Feb;21(2):244-246. doi: 10.1111/pbi.13954. Epub 2022 Dec 1.

Prem Kumar Ganesan^#^{1

2}, Rachel J Kulchar^#^{1

2}, Paul Kaznica^{1

2}, Ruben Montoya-Lopez^{1

2}, Brian J Green^{1

2}, Stephen J Streatfield^{1

2}, Henry Daniell^{1

2}

¹ Department of Basic and Translational Sciences, School of Dental Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
² Fraunhofer USA, Center Mid-Atlantic, Newark, Delaware, USA.

^# Contributed equally.

No abstract available

Keywords: biopharmaceutical; chloroplast; lettuce.

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