Photocatalytic aerobic oxidative functionalization (PAOF) reaction of benzyl alcohols by GO-MIL-100(Fe) composite in glycerol/K2CO3 deep eutectic solvent

Sepideh Abbasi; Mohammad Reza Naimi-Jamal; Shahrzad Javanshir; Akbar Heydari

doi:10.1038/s41598-022-22369-9

Photocatalytic aerobic oxidative functionalization (PAOF) reaction of benzyl alcohols by GO-MIL-100(Fe) composite in glycerol/K₂CO₃ deep eutectic solvent

Sci Rep. 2022 Oct 29;12(1):18214. doi: 10.1038/s41598-022-22369-9.

Authors

Sepideh Abbasi¹, Mohammad Reza Naimi-Jamal², Shahrzad Javanshir³, Akbar Heydari⁴

Affiliations

¹ Research Laboratory of Green Organic Synthesis and Polymers, Department of Chemistry, Iran University of Science and Technology (IUST), Tehran, 16846-13114, Iran.
² Research Laboratory of Green Organic Synthesis and Polymers, Department of Chemistry, Iran University of Science and Technology (IUST), Tehran, 16846-13114, Iran. naimi@iust.ac.ir.
³ Pharmaceutical and Heterocyclic Compounds Research Laboratory, Department of Chemistry, Iran University of Science and Technology, Tehran, 16846-13114, Iran.
⁴ Chemistry Department, Tarbiat Modares University, Tehran, 14155-4838, Iran.

Abstract

An MIL-100 (Fe)/graphene oxide (GO) hybrid, a fairly-known composite, was made through a simple one-step procedure and played a highlighted role in the photo-induced oxidative functionalization of the benzylic C-H bond. To identify the given binary composite, various techniques were applied: FT-IR, P-XRD, SEM, nitrogen absorption-desorption analysis, TGA, TEM, and UV-Visible DRS spectra. Proportions of GO used within the structure of the prepared composite differently ranged from low to high amount, and the most optimized ratio met at 38.5% of GO as the most efficient catalyst. Additionally, the reaction ran in Glycerol/K₂CO₃ (2:1) as the optimal solvent. The elemental roles of O₂^·- and OH^- were supposed to be the major ones for running a tandem oxidation-Knoevenagel reaction. The heterogeneity and reusability of the catalyst were also examined and confirmed after five successive runs.