Metastatic mucinous ovarian carcinoma simulating lung primary: an integrated diagnostic lesson

Abstract

We herein document a rare instance of primary mucinous ovarian carcinoma metastatic to the left lung, whose deceptive secondary derivation was already envisaged according to the spectacular thromboembolism involving small pulmonary vessels, thereby realizing a centrifugal and centripetal metastatizing loop. This presentation was indicative of dismal prognosis. A multimodal biomarker key approach is herein emphasized, which included close clinico-pathologic data integration.

Keywords: G12C; KRAS; lung; mucinous adenocarcinoma; ovary.