Like a Game of Chess, Every Move Matters: The Role of Antibodies in the Myasthenia Gravis Treatment Landscape

Prim Care Companion CNS Disord. 2022 Oct 27;24(6):AR21018AH3C. doi: 10.4088/PCC.AR21018AH3C.

Abstract

Symptoms and disease pathophysiology of myasthenia gravis (MG) vary considerably with each patient, and their individual preferences and priorities add to the need for individualized treatment of this autoimmune disease. Research in MG has grown substantially in recent years. New treatments have the potential of being both effective and well tolerated, addressing the trade-off of choosing either efficacy or tolerability when selecting treatments. Promising investigational treatments that may become available in the future may allow more patients than ever before to achieve an asymptomatic state, with the ultimate goal being to turn off abnormal antibody production.

MeSH terms

  • Humans
  • Myasthenia Gravis* / drug therapy
  • Receptors, Cholinergic* / therapeutic use

Substances

  • Receptors, Cholinergic