Krill Oil Supplementation Does Not Change Waist Circumference and Sagittal Abdominal Diameter in Overweight Women: A Pilot Balanced, Double-Blind, and Placebo-Controlled Clinical Trial

Int J Environ Res Public Health. 2022 Oct 20;19(20):13574. doi: 10.3390/ijerph192013574.

Abstract

An excess of body fat is one of the biggest public health concerns in the world, due to its relationship with the emergence of other health problems. Evidence suggests that supplementation with long-chain polyunsaturated fatty acids (omega-3) promotes increased lipolysis and the reduction of body mass. Likewise, this clinical trial aimed to evaluate the effects of supplementation with krill oil on waist circumference and sagittal abdominal diameter in overweight women. This pilot, balanced, double-blind, and placebo-controlled study was carried out with 26 women between 20 and 59 years old, with a body mass index >25 kg/m2. The participants were divided into the control (CG) (n = 15, 3 g/daily of mineral oil) and krill oil (GK) (n = 16, 3 g/daily of krill oil) groups, and received the supplementation for eight weeks. Food intake variables were obtained using a 24 h food recall. Anthropometric measurements (body mass, body mass index, waist circumference, and sagittal abdominal diameter) and handgrip strength were obtained. After the intervention, no changes were found for the anthropometric and handgrip strength variables (p > 0.05). Regarding food intake, differences were found for carbohydrate (p = 0.040) and polyunsaturated (p = 0.006) fatty acids, with a reduction in the control group and an increase in krill oil. In conclusion, supplementation with krill oil did not reduce the waist circumference and sagittal abdominal diameter. Therefore, more long-term studies with a larger sample size are necessary to evaluate the possible benefits of krill oil supplementation in overweight women.

Keywords: adiposity; anthropometry; food intake; krill oil.

Publication types

  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Animals
  • Carbohydrates
  • Dietary Supplements
  • Double-Blind Method
  • Euphausiacea*
  • Fatty Acids, Omega-3*
  • Female
  • Hand Strength
  • Humans
  • Middle Aged
  • Mineral Oil
  • Overweight / drug therapy
  • Sagittal Abdominal Diameter
  • Waist Circumference
  • Young Adult

Substances

  • Mineral Oil
  • Fatty Acids, Omega-3
  • Carbohydrates

Grants and funding

This study was financed in part by the The Brazilian National Council for Scientific and Technological Development (CNPq, Brazil, 312252/2019-6 and 434159/2018-2).