Radiologic findings of biliary complications post liver transplantation

Abdom Radiol (NY). 2023 Jan;48(1):166-185. doi: 10.1007/s00261-022-03714-y. Epub 2022 Oct 26.

Abstract

Liver transplantation is a potentially curative treatment for patients with acute liver failure, end-stage liver disease, and primary hepatic malignancy. Despite tremendous advancements in surgical techniques and immunosuppressive management, there remains a high rate of post-transplant complications, with one of the main complications being biliary complications. In addition to anastomotic leak and stricture, numerous additional biliary complications are encountered, including ischemic cholangiopathy due to the sole arterial supply of the bile ducts, recurrence of primary biliary disease, infections, biliary obstruction from stones, cast, or hemobilia, and less commonly cystic duct remnant mucocele, vanishing duct syndrome, duct discrepancy and kinking, post-transplant lymphoproliferative disorder, retained stent, and ampullary dysfunction. This article presents an overview of biliary anatomy and surgical techniques in liver transplantation, followed by a detailed review of post-transplant biliary complications with their corresponding imaging findings on multiple modalities with emphasis on magnetic resonance imaging and MR cholangiopancreatography.

Keywords: Biliary complication; Liver transplantation; MRCP; MRI; Magnetic resonance cholangiopancreatography; Pitfalls.

Publication types

  • Review

MeSH terms

  • Bile Ducts / pathology
  • Biliary Tract* / blood supply
  • Biliary Tract* / diagnostic imaging
  • Cholangiopancreatography, Magnetic Resonance
  • Cholestasis* / surgery
  • Humans
  • Liver
  • Liver Transplantation* / adverse effects
  • Postoperative Complications* / pathology