[Type IVa2 urinary lithiasis and associated pathologies: About 3 cases]

Nephrol Ther. 2022 Nov;18(6):570-574. doi: 10.1016/j.nephro.2022.08.001. Epub 2022 Oct 21.
[Article in French]

Abstract

Introduction: Urinary lithiasis is a very common condition. The morpho-constitutional analysis of urinary stones is important for etiological diagnosis. It guides the explorations and the specific management. Type IVa2 stones are rare, have particular morphology and correspond to very targeted pathologies. We propose to report our cases of patients diagnosed with type IVa2 urinary lithiasis.

Methods: Our retrospective work focused on three cases of patients with the morphological type of renal lithiasis IVa2, collected between 2008 and 2020 in the Medicine A Department of Charles Nicolle Hospital in Tunis.

Results: All three patients were female; average age 37.6 years. The clinical symptomatology was identical marked by renal colic with recurrent episodes. The presence of a type IVa2 stone, isolated or associated with other components, guided the etiological investigation to look for a secondary or primary cause of distal renal tubular acidosis. We retained the diagnosis of a primary hyperparathyroidism in one case and a primary Gougerot-Sjögren's syndrome in the second case, and probable in the last case.

Conclusion: Determination of urolithiasis nature (morphological and chemical), although carried out late, was of major interest to us and allowed us to make the diagnosis of distal tubular acidosis.

Keywords: Acidose tubulaire distale carbapatite; Analyse morpho-constitutionnelle; Carbapatite; Distal tubular acidosis; Morpho-constitutional analysis; Urolithiases; Urolithiasis.

Publication types

  • English Abstract

MeSH terms

  • Acidosis*
  • Acidosis, Renal Tubular* / complications
  • Acidosis, Renal Tubular* / diagnosis
  • Adult
  • Female
  • Humans
  • Male
  • Nephrolithiasis* / complications
  • Nephrolithiasis* / diagnosis
  • Retrospective Studies
  • Urolithiasis* / complications
  • Urolithiasis* / diagnosis