Entropy Information of Pulse Dynamics in Three Stages of Pregnancy

Nan Li; Jiarui Yu; Luqi Huang; Xiaobo Mao; Yuping Zhao; Yi Yu

doi:10.1155/2022/6542072

Entropy Information of Pulse Dynamics in Three Stages of Pregnancy

Evid Based Complement Alternat Med. 2022 Oct 14:2022:6542072. doi: 10.1155/2022/6542072. eCollection 2022.

Authors

Nan Li¹, Jiarui Yu¹, Luqi Huang^{1

2}, Xiaobo Mao¹, Yuping Zhao², Yi Yu³

Affiliations

¹ School of Electrical and Information Engineering, Zhengzhou University, Zhengzhou, China.
² China Academy of Chinese Medical Sciences, Beijing, China.
³ The Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China.

Abstract

The aim of the present study is to use entropy to explore the change of pulse generated by normal pregnant women with gestational. Firstly, the subjects were divided into early (E), middle (M), and late (L) three stages according to gestational age. Then, pulse signals of the Chi position of 90 pregnant women at different gestational ages were collected. Secondly, the four entropies, namely fuzzy entropy (FuEn), approximate entropy (ApEn), sample entropy (SamEn), and permutation entropy (PerEn), were applied to the analysis of the long-term pulse changes of the pregnancy. Finally, the related information about pulse in different stages of pregnancy is given by the analysis of four kinds of entropy. Furthermore, the statistical tests are conducted for further comparison, and the descriptive statistics and the results are presented. In addition, boxplots are employed to show the distribution of four entropies of pregnancy. This work has studied the changes in pulse during pregnancy from quantitative and qualitative aspects. Our results show that entropy improves the diagnostic value of pulse analysis during pregnancy and could be applied to facilitate noninvasive diagnosis of pregnant women's physiological signals in the future.