A stabilized CXCL9(74-103)-derived peptide selectively inhibits proliferation, adhesion and metastasis of tumor cells that express high levels of heparan sulfate

Int J Biol Macromol. 2022 Dec 1;222(Pt B):2808-2822. doi: 10.1016/j.ijbiomac.2022.10.060. Epub 2022 Oct 19.

¹ Laboratory of Molecular Immunology, Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, KU Leuven, 3000 Leuven, Belgium.
² Laboratory of Virology and Chemotherapy, Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, KU Leuven, 3000 Leuven, Belgium.
³ Laboratory of Immunobiology, Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, KU Leuven, 3000 Leuven, Belgium.
⁴ Laboratory of Molecular Immunology, Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, KU Leuven, 3000 Leuven, Belgium. Electronic address: sofie.struyf@kuleuven.be.

No abstract available

Keywords: Chondroitin sulfate; Colon carcinoma; Heparan sulfate; Melanoma; Peptide therapy.

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