In this paper, two types of polymer-stabilized blue-phase liquid crystals (PS-BPLCs) with different monomers were designed and prepared. The morphology, temperature range and electro-optical properties of the blue phases were studied and discussed. The temperature range of both types of PS-BPLC is greater than 110 °C, and both samples can be stabilized well at room temperature. The organosilicone monomer 3-methacryloxypropyltrimethoxysilane (KH570), which contains double bonds, was introduced to a blue-phase system for the first time. Regarding the electro-optical performance, the on-state voltage of the PS-BPLCs with the KH570 monomer is reduced to 30 V compared with traditional C12A monomer systems in which the on-state voltage is 75 V at 458 nm. Meanwhile, a fast response and suppressed hysteresis are obtained. These results are helpful to the application of displays and photonic devices.