Prevalence and Correlation of Vitamin D Levels with Hematological and Biochemical Parameters in Young Adults

Ann Clin Lab Sci. 2022 Sep;52(5):815-824.

Abstract

Objective: Vitamin D has a pivotal role in maintaining healthy bones and in the modulation of multiple physiologic processes. Vitamin D deficiency has become a global burden that affects all members of society. This study aimed to investigate the prevalence and correlation of vitamin D deficiency with hematological and biochemical parameters in young adult college students. Hundred and fourteen students (77 men and 37 women) were recruited.

Materials and methods: The socio-demographic and clinicopathologic features of the students were evaluated using a pre-tested and validated questionnaire, and samples were collected for complete blood count (CBC), vitamin D, calcium, parathyroid hormone, and phosphorus measurements.

Results: Vitamin D deficiency was more prevalent in men (53.2%) than in women (48.7%). Calcium and parathyroid hormone levels were within the normal range, and 26% and 22% of male and female participants, respectively, had low phosphorus levels. Vitamin D showed a positive correlation with calcium in men (r=0.3927; P=0.005) and women (r=0.4122; P=0.0566). Although, vitamin D status had no impact on most of CBC parameters, significant positive correlation was observed with eosinophils in women.

Conclusions: Vitamin D deficiency is very prevalent among college students, therefore health education and public awareness campaigns on the consequences of vitamin D deficiency on health and well-being are required.

Keywords: Vitamin D; calcium; parathyroid hormone; phosphorus.

MeSH terms

  • Calcium
  • Female
  • Humans
  • Male
  • Parathyroid Hormone
  • Phosphorus
  • Prevalence
  • Vitamin D Deficiency* / epidemiology
  • Vitamin D*
  • Vitamins
  • Young Adult

Substances

  • Vitamin D
  • Calcium
  • Parathyroid Hormone
  • Vitamins
  • Phosphorus