MicroCrystalline Tyrosine-adsorbed immunotherapy

Curr Opin Allergy Clin Immunol. 2022 Dec 1;22(6):413-420. doi: 10.1097/ACI.0000000000000859. Epub 2022 Oct 10.

Abstract

Purpose of review: The purpose of this article is to provide an overview of the literature pertaining to the use of MicroCrystalline Tyrosine (MCT) in the immunotherapy with an emphasis on recent developments.

Recent findings: In addition to significant effectiveness and safety profiles, additional aspects of interest such as booster immunotherapy concepts, sustained clinical effects, long-term efficacy and disease-modifying effects are being focused on in the recently published studies. The depot adjuvant MCT also shows potential in promising disease-challenge models such as for malaria and melanoma.

Summary: MCT-adsorbed immunotherapy products have been shown to provide convincing overall safety, tolerability and efficacy outcomes, as well in vulnerable groups such as children and asthmatic patients.

Publication types

  • Review

MeSH terms

  • Adjuvants, Immunologic / therapeutic use
  • Asthma* / therapy
  • Child
  • Humans
  • Immunologic Factors
  • Immunotherapy
  • Tyrosine* / chemistry

Substances

  • Tyrosine
  • Adjuvants, Immunologic
  • Immunologic Factors