Imaging of pediatric bone tumors: A COG Diagnostic Imaging Committee/SPR Oncology Committee White Paper

Kevin B Cederberg; Ramesh S Iyer; Apeksha Chaturvedi; M B McCarville; Janice D McDaniel; Jesse K Sandberg; Amer Shammas; Susan E Sharp; Helen R Nadel

doi:10.1002/pbc.30000

Imaging of pediatric bone tumors: A COG Diagnostic Imaging Committee/SPR Oncology Committee White Paper

Pediatr Blood Cancer. 2023 Jun;70 Suppl 4(Suppl 4):e30000. doi: 10.1002/pbc.30000. Epub 2022 Oct 17.

Authors

Kevin B Cederberg¹, Ramesh S Iyer², Apeksha Chaturvedi³, M B McCarville⁴, Janice D McDaniel^{5

6}, Jesse K Sandberg⁷, Amer Shammas⁸, Susan E Sharp⁹, Helen R Nadel⁷

Affiliations

¹ Department of Radiology, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
² Department of Radiology, Seattle Children's Hospital, Seattle, Washington, USA.
³ Division of Pediatric Radiology, Department of Imaging Sciences, University of Rochester Medical Center, Rochester, New York, USA.
⁴ Department of Diagnostic Imaging, St Jude Children's Research Hospital, Memphis, Tennessee, USA.
⁵ Department of Pediatric Radiology, Akron Children's Hospital, Akron, Ohio, USA.
⁶ Department of Radiology, Northeast Ohio Medical University, Rootstown, Ohio, USA.
⁷ Department of Pediatric Radiology, Lucile Packard Children's Hospital, Stanford University, Stanford, California, USA.
⁸ Division of Nuclear Medicine, Department of Diagnostic Imaging, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada.
⁹ Department of Radiology, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.

PMID: 36250990
PMCID: PMC10661611 (available on 2024-06-01)
DOI: 10.1002/pbc.30000

Abstract

Malignant primary bone tumors are uncommon in the pediatric population, accounting for 3%-5% of all pediatric malignancies. Osteosarcoma and Ewing sarcoma comprise 90% of malignant primary bone tumors in children and adolescents. This paper provides consensus-based recommendations for imaging in children with osteosarcoma and Ewing sarcoma at diagnosis, during therapy, and after therapy.

Keywords: Ewing sarcoma; bone tumor; osteosarcoma; radiology.

Publication types

Research Support, N.I.H., Extramural

MeSH terms

Adolescent
Bone Neoplasms* / pathology
Child
Diagnostic Imaging
Humans
Neuroectodermal Tumors, Primitive, Peripheral*
Osteosarcoma* / pathology
Sarcoma, Ewing* / diagnostic imaging
Sarcoma, Ewing* / therapy
Surface Plasmon Resonance

Grants and funding

U10 CA180886/CA/NCI NIH HHS/United States