Congenital Herpes Simplex Virus: A Histopathological View of the Placenta

Cureus. 2022 Sep 13;14(9):e29101. doi: 10.7759/cureus.29101. eCollection 2022 Sep.

Abstract

Congenital Herpes simplex virus (HSV) infection is considered a common pregnancy pathology that is not always easy to diagnose. This study aimed to present the spectrum of placental histopathological lesions in pregnancies complicated by HSV infection. MEDLINE and Google Scholar databases were searched using the keywords "HSV" and "placental histopathology" up to June 20, 2022. Study inclusion required presenting placental histopathological anomalies in pregnant women diagnosed with HSV infection antenatally, during labor, or postnatally. Herein, we briefly present placental pathogenesis conditions, which have been correlated with congenital HSV infection, providing clinicians with a short review describing herpetic placental pathology.

Keywords: congenital infection; hsv; placenta; placental histopathology; pregnancy.

Publication types

  • Review