Semiparametric methods for incomplete longitudinal count data with an application to health and retirement study

J Appl Stat. 2021 Jul 12;49(14):3513-3535. doi: 10.1080/02664763.2021.1951684. eCollection 2022.

Abstract

In this paper, we propose and explore a novel semiparametric approach to analyzing longitudinal count data. We address the issue of missingness in longitudinal data and propose a weighted generalized estimations equations approach to fitting marginal mean response models for count responses with dropouts. Also, we investigate a spline regression approach to approximating the curvilinear relationship between the mean response and covariates. The asymptotic properties of the proposed estimators are studied in some detail. The empirical properties of the estimators are investigated using Monte Carlo simulations. An application is also provided using actual survey data obtained from the Health and Retirement Study (HRS).

Keywords: Generalized estimating equation; inverse probability weight; longitudinal data; missing response; semiparametric method; spline regression.

Grants and funding

The research of Sanjoy Sinha is partially supported by a grant from the Natural Sciences and Engineering Research Council of Canada.