Hemangioma Genetics and Associated Syndromes

Julie Luu; Colleen H Cotton

doi:10.1016/j.det.2022.07.001

Hemangioma Genetics and Associated Syndromes

Dermatol Clin. 2022 Oct;40(4):393-400. doi: 10.1016/j.det.2022.07.001. Epub 2022 Sep 16.

Authors

Julie Luu¹, Colleen H Cotton²

Affiliations

¹ University of the Incarnate Word School of Osteopathic Medicine, 7615 Kennedy Hill Dr, San Antonio, TX 78235, USA.
² Department of Dermatology and Dermatologic Surgery, Medical University of South Carolina, 135 Rutledge Avenue, MSC 578, Charleston, SC 29425, USA. Electronic address: cotton.colleen@gmail.com.

PMID: 36243427
DOI: 10.1016/j.det.2022.07.001

Abstract

This article explores what is known regarding infantile hemangioma (IH) genetics. Despite a great deal of research on this topic, the relationship between IH genetics and pathogenesis has yet to be understood. This article also outlines the appropriate work-up and management of syndromes associated with specific presentations of IH.

Keywords: Arterial anomalies; Hemangiomatosis; Infantile hemangioma; LUMBAR; PHACE.

Publication types

Review

MeSH terms

Hemangioma* / genetics
Hemangioma, Capillary*
Humans
Infant
Neurocutaneous Syndromes* / genetics
Neurocutaneous Syndromes* / pathology