The efficacy of organo-selenium conjugated cellulose polymer dressing to inhibit Candida albicans biofilm formation

J Microbiol Methods. 2022 Nov:202:106598. doi: 10.1016/j.mimet.2022.106598. Epub 2022 Oct 13.

Abstract

Selenium covalently bonded to cellulose can catalyze the formation of superoxide radicals. Candida albicans, colonizes epithelial surfaces and can be a fatal infection in immunocompromised people. In this study, we demonstrated the ability of organo-selenium, covalently attached to cotton textile dressings to kill C. albicans biofilms.

Keywords: Antibiotic resistance; Antimicrobials; Candida albicans; Organo-selenium compounds; Selenium.

MeSH terms

  • Antifungal Agents / pharmacology
  • Bandages
  • Biofilms
  • Candida albicans*
  • Cellulose / pharmacology
  • Humans
  • Polymers
  • Selenium* / pharmacology

Substances

  • Selenium
  • Cellulose
  • Polymers
  • Antifungal Agents