Next-generation brain observatories

Christof Koch; Karel Svoboda; Amy Bernard; Michele A Basso; Anne K Churchland; Adrienne L Fairhall; Peter A Groblewski; Jérôme A Lecoq; Zachary F Mainen; Mackenzie W Mathis; Shawn R Olsen; John W Phillips; Alexandre Pouget; Shreya Saxena; Josh H Siegle; Anthony M Zador

doi:10.1016/j.neuron.2022.09.033

Next-generation brain observatories

Neuron. 2022 Nov 16;110(22):3661-3666. doi: 10.1016/j.neuron.2022.09.033. Epub 2022 Oct 13.

Authors

Christof Koch¹, Karel Svoboda², Amy Bernard³, Michele A Basso⁴, Anne K Churchland⁵, Adrienne L Fairhall⁶, Peter A Groblewski¹, Jérôme A Lecoq¹, Zachary F Mainen⁷, Mackenzie W Mathis⁸, Shawn R Olsen¹, John W Phillips¹, Alexandre Pouget⁹, Shreya Saxena¹⁰, Josh H Siegle¹¹, Anthony M Zador¹²

Affiliations

¹ MindScope Program, Allen Institute, Seattle, WA, USA.
² Allen Institute for Neural Dynamics, Seattle, WA, USA. Electronic address: karel.svoboda@alleninstitute.org.
³ The Kavli Foundation, Los Angeles, CA, USA.
⁴ Washington National Primate Research Center, University of Washington, Seattle, WA, USA.
⁵ David Geffen School of Medicine, UCLA, Los Angeles, CA, USA.
⁶ University of Washington, Seattle, WA, USA.
⁷ Champalimaud Centre for the Unknown, Lisboa, Portugal.
⁸ Brain Mind Institute, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.
⁹ Department of Basic Neuroscience, University of Geneva, Geneva, Switzerland.
¹⁰ University of Florida, Gainesville, FL, USA.
¹¹ Allen Institute for Neural Dynamics, Seattle, WA, USA.
¹² Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA.

PMID: 36240770
DOI: 10.1016/j.neuron.2022.09.033

Abstract

We propose centralized brain observatories for large-scale recordings of neural activity in mice and non-human primates coupled with cloud-based data analysis and sharing. Such observatories will advance reproducible systems neuroscience and democratize access to the most advanced tools and data.

MeSH terms

Animals
Brain*
Mice
Neurosciences*