An Evaluation of Antimicrobial, Anticancer, Anti-Inflammatory and Antioxidant Activities of Silver Nanoparticles Synthesized from Leaf Extract of Madhuca longifolia Utilizing Quantitative and Qualitative Methods

Molecules. 2022 Sep 28;27(19):6404. doi: 10.3390/molecules27196404.

Abstract

In the current decade, nanoparticles are synthesized using solvents that are environmentally friendly. A number of nanoparticles have been synthesized at room temperature using water as a solvent, such as gold (Au) and silver (Ag) nanoparticles. As part of nanotechnology, nanoparticles are synthesized through biological processes. Biological methods are the preferred method for the synthesis of inorganic nanoparticles (AgNPs) as a result of their simple and non-hazardous nature. Nanoparticles of silver are used in a variety of applications, including catalysts, spectrally selective coatings for solar absorption, optical objectives, pharmaceutical constituents, and chemical and biological sensing. Antimicrobial agents are among the top uses of silver nanoparticles. In the current study, silver nanoparticles were biologically manufactured through Madhuca longifolia, and their antibacterial activity against pathogenic microorganisms, anticancer, anti-inflammatory, and antioxidant activities were assessed. UV-Vis spectroscopy, XRD (X-ray diffraction), transmission electron microscopy, Zeta Potential, and FTIR were used to characterize silver nanoparticles. The current work describes a cheap and environmentally friendly method to synthesize silver nanoparticles from silver nitrate solution by using plant crude extract as a reducing agent.

Keywords: Madhuca longifolia; anti-inflammation; antibacterial; anticancer; antioxidation; silver nanoparticle.

MeSH terms

  • Anti-Bacterial Agents / chemistry
  • Anti-Infective Agents* / pharmacology
  • Anti-Inflammatory Agents / pharmacology
  • Antioxidants / chemistry
  • Antioxidants / pharmacology
  • Gold / chemistry
  • Madhuca*
  • Metal Nanoparticles* / chemistry
  • Plant Extracts / chemistry
  • Plant Extracts / pharmacology
  • Reducing Agents
  • Silver / pharmacology
  • Silver Nitrate
  • Solvents
  • Spectroscopy, Fourier Transform Infrared
  • Water
  • X-Ray Diffraction

Substances

  • Anti-Bacterial Agents
  • Anti-Infective Agents
  • Anti-Inflammatory Agents
  • Antioxidants
  • Plant Extracts
  • Reducing Agents
  • Solvents
  • Water
  • Silver
  • Gold
  • Silver Nitrate

Grants and funding

The authors would like to thank the Faculty of Medicine, Universiti Kebangsaan Malaysia for the approval and funding of this research (Approval code: FF-2020-016).