OSM/OSMR and Interleukin 6 Family Cytokines in Physiological and Pathological Condition

Francesca Lantieri; Tiziana Bachetti

doi:10.3390/ijms231911096

OSM/OSMR and Interleukin 6 Family Cytokines in Physiological and Pathological Condition

Int J Mol Sci. 2022 Sep 21;23(19):11096. doi: 10.3390/ijms231911096.

Authors

Francesca Lantieri¹, Tiziana Bachetti²

Affiliations

¹ Health Science Department (DISSAL), University of Genoa, Via Pastore 1, 16132 Genova, Italy.
² IRCCS Ospedale Policlinico San Martino, U.O. Proteomica e Spettrometria di Massa, Largo R. Benzi, 10, 16132 Genova, Italy.

Abstract

Oncostatin M (OSM) is a member of the interleukin-6 (IL-6) family of cytokines and can bind two different receptors, Leukemia inhibitory factor receptor (LIFR) and Oncostatin M receptor (OSMR), through a complex containing the common glycoprotein 130 (gp130) subunit [...].

Publication types

Editorial

MeSH terms

Cytokine Receptor gp130 / metabolism
Cytokines*
Interleukin-6* / metabolism
Oncostatin M / metabolism
Receptors, Cytokine / metabolism
Receptors, OSM-LIF
Receptors, Oncostatin M / metabolism

Substances

Cytokines
Interleukin-6
Receptors, Cytokine
Receptors, OSM-LIF
Receptors, Oncostatin M
Oncostatin M
Cytokine Receptor gp130