Use of anti-Müllerian hormone for understanding ovulatory dysfunction in polycystic ovarian syndrome

Abstract

Purpose of review: The aim of this review is to understand how anti-Müllerian hormone (AMH) contributes to ovulatory dysfunction in polycystic ovarian syndrome (PCOS).

Recent findings: In the last few years, new findings have emerged on AMH and its role on the central nervous system causing ovulatory dysfunction.

Summary: Anovulation is a prominent feature of PCOS. Women with anovulatory PCOS have higher AMH levels than in ovulatory PCOS. Higher levels of AMH may contribute to the pathophysiology of PCOS through central and peripheral actions. Once universal standardization is achieved to measure serum AMH, the benefits would be significant in diagnosing women with PCOS.