Revisiting Fisher-KPP model to interpret the spatial spreading of invasive cell population in biology

Heliyon. 2022 Sep 30;8(10):e10773. doi: 10.1016/j.heliyon.2022.e10773. eCollection 2022 Oct.

Abstract

In this paper, the homotopy analysis method, a powerful analytical technique, is applied to obtain analytical solutions to the Fisher-KPP equation in studying the spatial spreading of invasive species in ecology and to extract the nature of the spatial spreading of invasive cell populations in biology. The effect of the proliferation rate of the model of interest on the entire population is studied. It is observed that the invasive cell or the invasive population is decreased within a short time with the minimum proliferation rate. The homotopy analysis method is found to be superior to other analytical methods, namely the Adomian decomposition method, the homotopy perturbation method, etc. because of containing an auxiliary parameter, which provides us with a convenient way to adjust and control the region of convergence of the series solution. Graphical representation of the approximate series solutions obtained by the homotopy analysis method, the Adomian decomposition method, and the Homotopy perturbation method is illustrated, which shows the superiority of the homotopy analysis method. The method is examined on several examples, which reveal the ingenuousness and the effectiveness of the method of interest.

Keywords: Closed-form solution; Fisher-KPP equation; Homotopy analysis method; Region of convergence.