Mechanisms for maintaining information in working memory

Cogn Neurosci. 2022 Jul;13(3-4):218-219. doi: 10.1080/17588928.2022.2131750. Epub 2022 Oct 10.

Abstract

The review by Slotnick is valuable for raising the important question of how much the hippocampal activity induced by novel stimuli is due to mechanisms for encoding into long-term memory, and how much is due to working memory. Slotnick's paper implicitly defines working memory as being equivalent to sustained activation during the late delay period. In this commentary, we suggest that cognitive neuroscientists should consider a broader range of cellular and synaptic mechanisms for maintaining information in working memory.

Keywords: Working memory; cellular mechanisms; hippocampus; short-term potentiation.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Comment

MeSH terms

  • Hippocampus / physiology
  • Humans
  • Memory, Short-Term* / physiology
  • Neuronal Plasticity* / physiology