A case of central nervous system infection by Candida famata in an immunosuppressed patient with HIV-1 infection

Joao Caria; Ema Leal; Andre Dias; Helder Pinheiro; Diana Póvoas; Fernando Maltez

doi:10.1016/j.mmcr.2022.09.004

A case of central nervous system infection by Candida famata in an immunosuppressed patient with HIV-1 infection

Med Mycol Case Rep. 2022 Sep 28:38:21-24. doi: 10.1016/j.mmcr.2022.09.004. eCollection 2022 Dec.

Authors

Joao Caria¹, Ema Leal¹, Andre Dias¹, Helder Pinheiro¹, Diana Póvoas¹, Fernando Maltez¹

Affiliation

¹ Serviço de Doenças Infeciosas do Hospital de Curry Cabral, Centro Hospitalar Universitario de Lisboa Central, R. da Beneficencia 8, Lisboa, 1050-099, Portugal.

Abstract

Invasive fungal infections caused by Candida species are increasingly observed in immunosuppressed patients. Candida albicans is the more often identified species and neurocandidiasis is associated with high mortality rates. Diagnosis and treatment of these infections are frequently challenging. We report a case of central nervous system infection caused by Candida famata in an HIV-1 infected patient. To our best knowledge this is just the second published case of neural infection by this agent.

Keywords: ART, Antiretroviral therapy; CD4+, cluster of differentiation 4; CNS, Central nervous system; Candida famata; Central nervous system infection; Epidural abscess; HIV; HIV, Human immunodeficiency virus; Immunosuppressed.

Publication types

Case Reports