Negative Predictive Value of the Rapid Test Ag 2019-nCoV During the Predominance of Omicron over the Delta Variant and Implications in the Emergency Department

Barbara Fyntanidou; Georgios Meletis; Sofia Gkarmiri; Ioanna Gkeka; Areti Tychala; Lemonia Skoura

doi:10.1007/s42399-022-01294-y

Negative Predictive Value of the Rapid Test Ag 2019-nCoV During the Predominance of Omicron over the Delta Variant and Implications in the Emergency Department

SN Compr Clin Med. 2022;4(1):213. doi: 10.1007/s42399-022-01294-y. Epub 2022 Sep 27.

Authors

Barbara Fyntanidou¹, Georgios Meletis², Sofia Gkarmiri¹, Ioanna Gkeka², Areti Tychala¹, Lemonia Skoura²

Affiliations

¹ Department of Emergency Medicine, AHEPA University Hospital, S. Kiriakidi str. 1, 54636 Thessaloniki, Greece.
² Department of Microbiology, AHEPA University Hospital, Thessaloniki, Greece.

Abstract

The high prevalence of asymptomatic patients infected with SARS-CoV-2 during the pandemic peaks and the common occurrence of in-hospital transmission urges the need for SARS-CoV-2 testing before admission of all patients with non-COVID-related symptoms. RT-PCR testing however is costly, time-consuming, and increases the length of stay in the emergency department. For the aforementioned reasons, we propose that the admission of non-suspected COVID-19 patients to the appropriate department should be based on the sole use of the rapid test result. In order to assess the safety of this suggestion, we assessed the negative predictive value of our rapid antigen tests that was calculated at 96.38%. This value was considered acceptable and the proposed strategy was applied in our hospital improving the overall turnaround times. However, since various rapid tests may perform differently, we propose that hospitals assess their own methodologies before implementing our proposal.

Keywords: COVID-19; Delta; Omicron; Rapid test; SARS-CoV-2.

Publication types

Editorial