α-Connexin Carboxyl Terminal Peptide 1 Attenuates Ischemia-Reperfusion Injury in Liver Transplantation With Extended Cold Preservation by Stabilizing Cell Junctions in Mice

Yuefan Wang; Biao Lei; Yonglong Pan; Chen Su; Weijian Wang; Haoquan Zhang; Feng Xia; Peng Zhu; Songqing He; Qi Cheng

doi:10.1016/j.transproceed.2022.08.033

α-Connexin Carboxyl Terminal Peptide 1 Attenuates Ischemia-Reperfusion Injury in Liver Transplantation With Extended Cold Preservation by Stabilizing Cell Junctions in Mice

Transplant Proc. 2022 Oct;54(8):2364-2373. doi: 10.1016/j.transproceed.2022.08.033. Epub 2022 Sep 30.

Authors

Yuefan Wang¹, Biao Lei², Yonglong Pan¹, Chen Su¹, Weijian Wang¹, Haoquan Zhang¹, Feng Xia¹, Peng Zhu³, Songqing He⁴, Qi Cheng⁵

Affiliations

¹ Hepatic Surgery Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China; Hubei Key Laboratory of Hepato-Pancreato-Biliary Diseases, Wuhan, Hubei, China.
² Department of Hepatobiliary Surgery, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China; Key Laboratory of Early Prevention and Treatment for Regional High Frequency Tumor, Ministry of Education, Nanning, Guangxi, China; Guangxi Key Laboratory of Early Prevention and Treatment for Regional High Frequency Tumor, Nanning, Guangxi, China.
³ Hepatic Surgery Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China; Hubei Key Laboratory of Hepato-Pancreato-Biliary Diseases, Wuhan, Hubei, China; Key Laboratory of Organ Transplantation, Ministry of Education, Wuhan, Hubei, China; Key Laboratory of Organ Transplantation, Chinese Academy of Medical Sciences, Wuhan, Hubei, China. Electronic address: zhupeng@tjh.tjmu.edu.cn.
⁴ Department of Hepatobiliary Surgery, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China; Key Laboratory of Early Prevention and Treatment for Regional High Frequency Tumor, Ministry of Education, Nanning, Guangxi, China; Guangxi Key Laboratory of Early Prevention and Treatment for Regional High Frequency Tumor, Nanning, Guangxi, China. Electronic address: dr_hesongqing@163.com.
⁵ Hepatic Surgery Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China; Hubei Key Laboratory of Hepato-Pancreato-Biliary Diseases, Wuhan, Hubei, China; Key Laboratory of Organ Transplantation, Ministry of Education, Wuhan, Hubei, China; Key Laboratory of Organ Transplantation, Chinese Academy of Medical Sciences, Wuhan, Hubei, China. Electronic address: chengqi@hust.edu.cn.

PMID: 36184342
DOI: 10.1016/j.transproceed.2022.08.033

No abstract available

MeSH terms

Animals
Cold Temperature
Connexins
Intercellular Junctions
Liver / surgery
Liver Transplantation* / adverse effects
Mice
Organ Preservation
Organ Preservation Solutions*
Peptides
Reperfusion Injury* / etiology
Reperfusion Injury* / prevention & control

Substances

Connexins
Peptides
Organ Preservation Solutions