Microwave-assisted direct synthesis of BODIPY dyes and derivatives

Org Biomol Chem. 2022 Nov 30;20(46):9132-9137. doi: 10.1039/d2ob01349e.

Abstract

A microwave-assisted one-pot synthesis of BODIPY dyes from pyrroles and acyl chlorides is reported. This protocol features short reaction times, low temperatures, minimum amount of solvent, scalability, versatility, and good yields of the products. These simple, efficient and sustainable conditions can be also applied to the synthesis of derivatives such as BOPHY, BOAHY and BOPAHY.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Chlorides
  • Coloring Agents*
  • Microwaves*
  • Solvents

Substances

  • 4,4-difluoro-4-bora-3a,4a-diaza-s-indacene
  • Coloring Agents
  • Solvents
  • Chlorides