Fluids in the ICU: which is the right one?

Nephrol Dial Transplant. 2023 Jun 30;38(7):1603-1612. doi: 10.1093/ndt/gfac279.

Abstract

The administration of fluids is one of the most common interventions in the intensive care unit. The effects and side effects of intravenous fluids depend on the amount administered and their specific composition. Intravenous fluid solutions are either considered crystalloids (for example 0.9% saline, lactated Ringer's solution) or colloids (artificial colloids such as gelatins, and albumin). This narrative review summarizes the physiological principles of fluid therapy and reviews the most important studies on crystalloids, artificial colloids and albumin in the context of critically ill patients.

Keywords: albumin; colloids; critically ill; crystalloids, intravenous fluids.

Publication types

  • Review

MeSH terms

  • Albumins* / therapeutic use
  • Colloids* / therapeutic use
  • Crystalloid Solutions
  • Humans
  • Intensive Care Units
  • Isotonic Solutions / adverse effects
  • Isotonic Solutions / therapeutic use

Substances

  • Isotonic Solutions
  • Crystalloid Solutions
  • Albumins
  • Colloids