Intraflagellar transport: Derailing causes turnarounds

Aniruddha Mitra; Erwin J G Peterman

doi:10.1016/j.cub.2022.07.061

Intraflagellar transport: Derailing causes turnarounds

Curr Biol. 2022 Sep 26;32(18):R967-R969. doi: 10.1016/j.cub.2022.07.061.

Authors

Aniruddha Mitra¹, Erwin J G Peterman²

Affiliations

¹ Department of Physics and Astronomy, and LaserLaB Amsterdam, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
² Department of Physics and Astronomy, and LaserLaB Amsterdam, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands. Electronic address: e.j.g.peterman@vu.nl.

PMID: 36167049
DOI: 10.1016/j.cub.2022.07.061

Abstract

In intraflagellar transport, protein complexes travel along cilia from base to tip without stopping and change direction only at the tip. A new study shows that this directional change does not depend on any tip-associated machinery.

Publication types

Comment

MeSH terms

Biological Transport
Cilia* / metabolism
Flagella* / metabolism
Protein Transport